Year : 2014  |  Volume : 8  |  Issue : 3  |  Page : 368-373

Pain relief in day care arthroscopic knee surgery: A comparison between intra-articular ropivacaine and levobupivacaine: A prospective, double-blinded, randomized controlled study

1 Department of Anaesthesiology, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India
2 Department of Anaesthesiology, NRS Medical College, Kolkata, West Bengal, India
3 Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
4 Department of Anaesthesiology, Bangur Institute of Neurology, Kolkata, West Bengal, India
5 Department of Orthopedics, R.G. Kar Medical College, Kolkata, West Bengal, India
6 Department of G & O, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India

Correspondence Address:
Dr. Anjan Das
174, Gorakshabashi Road, Royal Plaza Apartment, 4th Floor, Flat No. 1, Nagerbazar, Kolkata - 700 028, West Bengal
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Source of Support: None, Conflict of Interest: None

Read associated Notice of Retraction: Retraction with this article

DOI: 10.4103/1658-354X.136435

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Background: Post-operative pain frequently hampers implementation of day care arthroscopic knee surgery in spite of so many analgesic, local anesthetic drugs and routes of administration. Aims: The aim of the present study was carried out to compare the efficacy of ropivacaine and levobupivacaine when administered through intra-articular route in controlling pain after day care arthroscopic knee surgery. Setting and Design: It was a prospective, double-blinded and randomized controlled study. Materials and Methods: April 2008-December 2008, 60 patients of both sex, of American Society of Anesthesiologists physical status I and II, undergoing day care arthroscopic knee surgery were randomly assigned into two groups (R, L). Group R received 10 ml of 0.75% ropivacaine, whereas group L received 10 ml of 0.50% levobupivacaine through intra-articular route at the end of the procedure. Pain assessed using visual analog scale (VAS) and diclofenac sodium given as rescue analgesia when VAS >3. Time of first analgesic request and total rescue analgesic were calculated. Statistical Analysis and Results: based on comparable demographic profiles; time for the requirement of first post-operative rescue analgesia (242.16 ± 23.86 vs. 366.62 ± 24.42) min and total mean rescue analgesic requirement was (104.35 ± 18.96 vs. 76.82 ± 14.28) mg in group R and L respectively. Group R had higher mean VAS score throughout the study period. No side effects found among the groups. These two results were clinically and statistically significant (P < 0.05). Conclusion: Hence, it was evident that intra-articular levobupivacaine give better post-operative pain relief, with an increase in time of first analgesic request and decreased need of total post-operative analgesia compared with ropivacaine.

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