| CASE REPORT |
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| Year : 2013 | Volume
: 7
| Issue : 3 | Page : 350-352 |
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Obstetric use of nitroglycerin: Anesthetic implications
Richa Saroa1, Shikha Sachan2, Sanjeev Palta1, Satinder Gombar1, Nitika Sahai1
1 Department of Anesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India
2 SGRRIM and HS, Dehradun, India
Correspondence Address:
Richa Saroa
1208, Sector 32, Chandigarh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1658-354X.115338
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Nitroglycerin has been used in anesthetic practice for induced hypotension and managing perioperative hypertension and myocardial ischemia. Contrary to the continuous low dose infusions (5-20 mcg/min) used for the same, intravenous bolus dosages are sometimes administered at the behest of obstetricians for removal of retained placenta. Use of nitroglycerine in managing retained placenta is undertaken as a last resort when other measures fail to relax the uterine smooth muscles. Intravenous nitroglycerine relaxes smooth muscle cells by releasing nitric oxide thus causing prompt cervico-uterine relaxation. However, administration of nitroglycerine in this manner is not without risks which should be kept in mind while using it for obstetric purposes. We hereby report a case of 22-year-old female scheduled for manual removal of placenta where unpredictable and unexpected hypoxemia was observed following nitroglycerine administration. |
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