REVIEW ARTICLE
Year : 2013  |  Volume : 7  |  Issue : 3  |  Page : 322-326

Tapentadol hydrochloride: A novel analgesic


Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Pondicherry, India

Correspondence Address:
Dewan Roshan Singh
Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Pondicherry 607 402
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1658-354X.115319

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Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat acute, chronic, and neuropathic pain.


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