CASE REPORT
Year : 2018  |  Volume : 12  |  Issue : 4  |  Page : 640-642

Multidisciplinary team approach for an atypical presentation of postpartum thrombotic thrombocytopenic purpura and severe preeclampsia in the Intensive Care Unit


1 Department of Anesthesia, Pain Management and Perioperative Medicine, Detroit, Michigan, USA
2 Department of Transfusion Medicine, Henry Ford Hospital, Detroit, Michigan, USA
3 Division of Critical Care, Department of Anesthesia, Pain Management and Perioperative Medicine, Henry Ford Hospital, Detroit, Michigan, USA

Correspondence Address:
Dr. Jose R Navas-Blanco
Department of Anesthesia and Perioperative Medicine, Henry Ford Hospital, 2799 West Grand Boulevard, CFP-341, Detroit, Michigan 48202
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/sja.SJA_204_18

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Thrombotic thrombocytopenic purpura (TTP) is a rare hematologic syndrome during pregnancy with overlapping features of severe preeclampsia and is associated with high morbidity and mortality. We present a case of postpartum TTP, associated with severe preeclampsia. Therapeutic approach for this case included corticosteroids, plasma exchange therapy, and immunomodulatory therapy. We describe the pathophysiology of TTP in pregnancy and its similarities with other disorders that constitute the thrombotic microangiopathy syndrome, as well as other clinical factors which made the final diagnosis challenging. In addition, we highlight the value of a multidisciplinary team care approach to assure an optimal outcome for this clinical scenario.


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