CASE REPORT
Year : 2013  |  Volume : 7  |  Issue : 3  |  Page : 350-352

Obstetric use of nitroglycerin: Anesthetic implications


1 Department of Anesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India
2 SGRRIM and HS, Dehradun, India

Correspondence Address:
Richa Saroa
1208, Sector 32, Chandigarh
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1658-354X.115338

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Nitroglycerin has been used in anesthetic practice for induced hypotension and managing perioperative hypertension and myocardial ischemia. Contrary to the continuous low dose infusions (5-20 mcg/min) used for the same, intravenous bolus dosages are sometimes administered at the behest of obstetricians for removal of retained placenta. Use of nitroglycerine in managing retained placenta is undertaken as a last resort when other measures fail to relax the uterine smooth muscles. Intravenous nitroglycerine relaxes smooth muscle cells by releasing nitric oxide thus causing prompt cervico-uterine relaxation. However, administration of nitroglycerine in this manner is not without risks which should be kept in mind while using it for obstetric purposes. We hereby report a case of 22-year-old female scheduled for manual removal of placenta where unpredictable and unexpected hypoxemia was observed following nitroglycerine administration.


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