ARTICLE
Year : 2007  |  Volume : 1  |  Issue : 1  |  Page : 5

Assessment of perioperative transfusion therapy and complications in sickle cell disease patients undergoing surgery


1 College of Medicine and Medical Science, Arabian Gulf University and Anesthesia Department, Salmaniya Medical Complex, Bahrain
2 Faculty of Medicine, Zagazig University, Egypt and Consultant anesthetist, Anesthesia Department, Salmaniya Medical Complex, Bahrain
3 Anesthesia Department, Salmaniya Medical Complex, Bahrain

Correspondence Address:
Zahra M Al-Sammak
College of Medicine and Medical Science, Arabian Gulf University and Anesthesia Department, Salmaniya Medical Complex
Bahrain
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Background : Perioperative blood transfusion is usually given to sickle cell disease patients to reduce or prevent perioperative morbidity. Assessment of such a practice was the subject of our study. Methods : A retrospective one year survey of sickle cell disease patients undergoing surgery at Salmaniya Medical Complex, Bahrain, was conducted. The medical records were reviewed to characterize the surgical procedure, transfusion management and perioperative complications. Results : 85 sickle cell disease patients who underwent surgery were studied. Preoperatively, 21.2% had exchange transfusion (ETX), 24.7% had simple transfusion (STX) and 54.1% had no transfusion (NTX). 14.1% of all patients had postoperative complications and 50% of those who had complications were from the laparoscopic cholecystectomy group. The incidence of sickle cell crisis postoperatively was 22.2% in ETX group, 9.5% in STX group and 4.34% in the NTX group. The incidence of acute chest syndrome postoperatively was found to be 5.55 % in the ETX group, 4.76% in the STX group and 4.34% in the NTX group. No intraoperative complications were recorded in all groups. All patients who had postoperative complications had a preoperative HBSS > 40%. Conclusion : Exchange transfusion doesn't prevent perioperative complications of sickle cell disease. HBSS > 40% carries a higher risk of postoperative complications.


[FULL TEXT] [PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2056    
    Printed181    
    Emailed1    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal